| 產(chǎn)品描述： | INH6, an effective Hec1 inhibitor, selectively disrupts the Hec1/Nek2 interaction and induces chromosome mis-alignment. |
| 靶點： |
Apoptosis;Microtubule Associated;Apoptosis;MicrotubuleAssociated |
| 細胞實驗： |
Standard XTT assays with a four-day drug treatment procedure are performed to measure the dose-dependent cytotoxicity of INH analogs in cultured cells. Triplicate sets are measured and compiled for final data presentation. The assay is performed by using a commercial kit following the instructions. In principle, cells are plated on 96-well dishes one day before the drug treatment, followed by drug treatment on day 2 and XTT assay on day 5 after drug addition. The absorption at 595 nm is measured with a plate reader and converted to cell survival percentages in comparison to mock treated groups.(Only for Reference) |
| 參考文獻： |
1. Qiu XL, et al. J Med Chem. 2009, 52(6), 1757-1767. |
| 溶解性： |
Soluble in DMSO、Ethanol |
| 保存條件： |
-20℃ |
| 配置溶液濃度參考： |
|
1mg |
5mg |
10mg |
| 1 mM |
3.102 ml |
15.508 ml |
31.015 ml |
| 5 mM |
0.62 ml |
3.102 ml |
6.203 ml |
| 10 mM |
0.31 ml |
1.551 ml |
3.102 ml |
| 50 mM |
0.062 ml |
0.31 ml |
0.62 ml |
|
| 注意： |
部分產(chǎn)品我司僅能提供部分信息，我司不保證所提供信息的權威性，僅供客戶參考交流研究之用。 |
上海工商
危險品化學品經(jīng)營許可證（不帶存儲）
營業(yè)執(zhí)照(三證合一)
北京