日韩欧美 a级,国产又色又爽又刺激在线观看,偷偷色噜狠狠狠狠的777米奇,浮妇高潮喷白浆视频

  1. 首頁(yè) > 小分子化合物 > 信號(hào)通路 > 細(xì)胞凋亡 > BAY 80-6946 (Copanlisib)

BAY 80-6946 (Copanlisib)

    
98%

BAY 80-6946 (Copanlisib)

源葉(MedMol)
S80039 一鍵復(fù)制產(chǎn)品信息
1032568-63-0
C23H28N8O4
480.52
2-氨基-N-[2,3-二氫-7-甲氧基-8-[3-(4-嗎啉基)丙氧基]咪唑并[1,2-C]喹唑啉-5-基]-5-嘧啶甲酰胺;BAY 80-6946; 2-Amino-N.N-diaethyl-toluolsulfonamid-(4); 2-amino-N-[7-methoxy-8-(3-morpholin-4-ylpropoxy)-2,3-dihydroimidazo-[1,2-c]quina
貨號(hào) 規(guī)格 價(jià)格 上海 北京 武漢 南京 購(gòu)買(mǎi)數(shù)量
S80039-1mg 98% ￥290.00 4 - - -
S80039-2mg 98% ￥500.00 5 - - -
S80039-5mg 98% ￥930.00 5 - - -
S80039-10mg 98% ￥1490.00 5 - - -
S80039-25mg 98% ￥2750.00 6 - - -
S80039-50mg 98% ￥4100.00 5 - - -
S80039-100mg 98% ￥5800.00 5 - - -
產(chǎn)品介紹 參考文獻(xiàn) 質(zhì)檢證書(shū)(COA) 摩爾濃度計(jì)算器 相關(guān)產(chǎn)品

產(chǎn)品介紹

Copanlisib (BAY 80-6946) is a potent, selective and ATP-competitive pan-class I PI3K inhibitor, with IC50s of 0.5 nM, 0.7 nM, 3.7 nM and 6.4 nM for PI3Kα, PI3Kδ, PI3Kβ and PI3Kγ, respectively. Copanlisib has more than 2,000-fold selectivity against other lipid and protein kinases, except for mTOR. Copanlisib has superior antitumor activity

產(chǎn)品描述： Copanlisib (BAY 80-6946) is a potent, selective and ATP-competitive pan-class I PI3K inhibitor, with IC50s of 0.5 nM, 0.7 nM, 3.7 nM and 6.4 nM for PI3Kα, PI3Kδ, PI3Kβ and PI3Kγ, respectively. Copanlisib has more than 2,000-fold selectivity against other lipid and protein kinases, except for mTOR. Copanlisib has superior antitumor activity
靶點(diǎn)： PI3Kα：0.5 nM (IC50)；PI3Kβ：3.7 nM (IC50)；PI3Kδ：0.7 nM (IC50)；PI3Kγ：6.4 nM (IC50)；mTOR：45 nM (IC50);Apoptosis;PI3K
體內(nèi)研究： Copanlisib (BAY 80-6946; 0.5-6 mg/kg; intravenous injection; every second day, every third day; for 60 days; athymic nude rats) treatment displays robust antitumor activity in the rat KPL4 tumor xenograft model
參考文獻(xiàn)： 1. Liu N, et al. BAY 80-6946 is a highly selective intravenous PI3K inhibitor with potent p110α and p110δ activities in tumor cell lines and xenograft models. Mol Cancer Ther. 2013 Nov;12(11):2319-30.
溶解性： 1M  HCl  :  100  mg/mL  (208.11  mM;  Need  ultrasonic)
保存條件： -20℃
配置溶液濃度參考：
1mg 5mg 10mg
1 mM 2.081 ml 10.405 ml 20.811 ml
5 mM 0.416 ml 2.081 ml 4.162 ml
10 mM 0.208 ml 1.041 ml 2.081 ml
50 mM 0.042 ml 0.208 ml 0.416 ml
注意： 部分產(chǎn)品我司僅能提供部分信息，我司不保證所提供信息的權(quán)威性，僅供客戶(hù)參考交流研究之用。

參考文獻(xiàn)

質(zhì)檢證書(shū)(COA)

如何獲取質(zhì)檢證書(shū)(COA)?
請(qǐng)輸入貨號(hào)和一個(gè)與之匹配的批號(hào)。
例如:
批號(hào)：JS298415 貨號(hào)：S20001-25g
在貨品標(biāo)簽上如何找到貨號(hào)和批號(hào)?

摩爾濃度計(jì)算器

質(zhì)量 (mg) = 濃度 (mM) x 體積 (mL) x 分子摩爾量 (g/mol)

=
×
×

相關(guān)產(chǎn)品