產(chǎn)品介紹
BMS-794833 is a VEGFR2 and Met inhibitor extracted from patent WO2009094417, compound example 1; has IC50s of 15 and 1.7 nM, respectively.
產(chǎn)品描述： BMS-794833 is a VEGFR2 and Met inhibitor extracted from patent WO2009094417, compound example 1; has IC50s of 15 and 1.7 nM, respectively.
靶點：
VEGFR2:15 nM (IC50);Met:1.7 nM (IC50);VEGFR;c-Met/HGFR
體內(nèi)研究：
BMS-794833 is active by greater than 50% tumor growth inhibition for at least one tumor doubling time in the GTL-16 gastric carcinoma model. No toxicity is observed at any of the dose levels when administered once daily for a duration of 14 days
參考文獻(xiàn)：
1. WO2009094417
溶解性：
Soluble in DMSO
保存條件：
-20℃
配置溶液濃度參考：
1mg 5mg 10mg
1 mM 2.133 ml
10.665 ml
21.329 ml
5 mM 0.427 ml
2.133 ml
4.266 ml
10 mM 0.213 ml
1.066 ml
2.133 ml
50 mM 0.043 ml
0.213 ml
0.427 ml
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危險品化學(xué)品經(jīng)營許可證（不帶存儲）
營業(yè)執(zhí)照(三證合一)
北京