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Cyclo(-Arg-Gly-Asp-D-Phe-Lys)

    98%

Cyclo(-Arg-Gly-Asp-D-Phe-Lys)

源葉(MedMol)
S80423
161552-03-0
C27H41N9O7
603.671
c(D-Phe-Lys-Arg-Gly-Asp); A8164; cyclic-RGD peptide; cyclo-[Arg-Gly-Asp-D-Phe-Lys]; Cyclo (-RGDfK); cyclo[RGD-{D-F}-K];
品牌 貨號(hào) 產(chǎn)品規(guī)格 價(jià)格(RMB) 庫(kù)存(上海) 北京 武漢 南京 購(gòu)買數(shù)量
源葉(MedMol) S80423-5mg 98% ¥560.00元 >10 - - -
源葉(MedMol) S80423-10mg 98% ¥960.00元 >10 - - -
源葉(MedMol) S80423-25mg 98% ¥1600.00元 >10 - - -
產(chǎn)品介紹 參考文獻(xiàn) 質(zhì)檢證書(shū)(COA) 摩爾濃度計(jì)算器 相關(guān)產(chǎn)品

產(chǎn)品介紹

Cyclo(-RGDfK) is a potent and selective inhibitor of the αvβ3 integrin, with an IC50 of 0.94 nM. Cyclo(-RGDfK) TFA potently targets tumor microvasculature and cancer cells through the specific binding to the αvβ3 integrin on the cell surface
產(chǎn)品描述: Cyclo(-RGDfK) is a potent and selective inhibitor of the αvβ3 integrin, with an IC50 of 0.94 nM. Cyclo(-RGDfK) TFA potently targets tumor microvasculature and cancer cells through the specific binding to the αvβ3 integrin on the cell surface
靶點(diǎn): αvβ3:0.94 nM (IC50);Integrin
參考文獻(xiàn): 1. Simecek J, et al. Benefits of NOPO as chelator in gallium-68 peptides, exemplified by preclinical characterization of (68)Ga-NOPO-c(RGDfK). Mol Pharm. 2014 May 5;11(5):1687-95. 2. Lopez-Rodriguez V, et al. Preparation and preclinical evaluation of (66)Ga-DOTA-E(c(RGDfK))2 as a potential theranostic radiopharmaceutical. Nucl Med Biol. 2015 Feb;42(2):109-14.
溶解性: DMSO  :  125  mg/mL  (207.07  mM;  Need  ultrasonic)    H2O  :  50  mg/mL  (82.83  mM;  Need  ultrasonic)
保存條件: 2-8℃
配置溶液濃度參考:
1mg 5mg 10mg
1 mM 1.657 ml 8.283 ml 16.565 ml
5 mM 0.331 ml 1.657 ml 3.313 ml
10 mM 0.166 ml 0.828 ml 1.657 ml
50 mM 0.033 ml 0.166 ml 0.331 ml
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參考文獻(xiàn)

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