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Secnidazole 99%(HPLC)

Secnidazole

源葉(MedMol)
S80653
3366-95-8
C7H11N3O3
185.18
品牌 貨號(hào) 產(chǎn)品規(guī)格 價(jià)格(RMB) 庫存（上海） 北京 武漢 南京 購買數(shù)量
源葉(MedMol) S80653-10mg 99%(HPLC) ￥120.00元 >10 - - -
源葉(MedMol) S80653-50mg 99%(HPLC) ￥320.00元 >10 - - -
產(chǎn)品介紹 參考文獻(xiàn) 質(zhì)檢證書(COA) 摩爾濃度計(jì)算器 相關(guān)產(chǎn)品

產(chǎn)品介紹

Secnidazole (RP-14539) is an orally active azole antibiotic and a imidazole mitigator of Serratia marcescens virulence. Secnidazole, as an analog of acylhomoserine lactones, effectively inhibits QS resulting in the attenuation of Pseudomonas aeruginosa pathogenesis. Secnidazole has antimicrobial activity against many anaerobic Gram-negative and Gram-positive bacterial species in vitro. Secnidazole can be used for the research of various diseases, such as amoebiasis and giardiasis, and bacterial vaginitis
產(chǎn)品描述： Secnidazole (RP-14539) is an orally active azole antibiotic and a imidazole mitigator of Serratia marcescens virulence. Secnidazole, as an analog of acylhomoserine lactones, effectively inhibits QS resulting in the attenuation of Pseudomonas aeruginosa pathogenesis. Secnidazole has antimicrobial activity against many anaerobic Gram-negative and Gram-positive bacterial species in vitro. Secnidazole can be used for the research of various diseases, such as amoebiasis and giardiasis, and bacterial vaginitis
靶點(diǎn)： Amebae;Antibiotic;Parasite
體內(nèi)研究：
Secnidazole (100 μL; ip.; for 5 days) has protective activity against S.marcescens pathogenesis and can diminish its pathogenesis in mice
參考文獻(xiàn)：
1. Secnidazole. LiverTox: Clinical and Research Information on Drug-Induced Liver Injury, National Institute of Diabetes and Digestive and Kidney Diseases, 25 February 2020. 2. Helen S Pentikis, et al. In vitro metabolic profile and drug-drug interaction assessment of secnidazole, a high-dose 5-nitroimidazole antibiotic for the treatment of bacterial vaginosis. Pharmacol Res Perspect. 2020 Aug;8(4):e00634. 3. Ahdab N Khayyat, et al. Secnidazole Is a Promising Imidazole Mitigator of Serratia marcescens Virulence. Microorganisms. 2021 Nov 11;9(11):2333.
溶解性： DMSO  :  ≥  30  mg/mL  (162.00  mM)    H2O  :  25  mg/mL  (135.00  mM;  Need  ultrasonic)
保存條件： -20℃
配置溶液濃度參考：
1mg 5mg 10mg
1 mM 5.4 ml 27.001 ml 54.002 ml
5 mM 1.08 ml 5.4 ml 10.8 ml
10 mM 0.54 ml 2.7 ml 5.4 ml
50 mM 0.108 ml 0.54 ml 1.08 ml
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摩爾濃度計(jì)算器

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