| 產(chǎn)品描述： | Lincomycin hydrochloride monohydrate is a narrow-spectrum antibiotic, has similar effects to erythromycin, which has a good effect on gram-positive coccus, mainly used to inhibit the synthesis of bacterial cell protein |
| 靶點(diǎn)： |
Bacterial;Antibiotic;ribosome;Antibacterial;Antibiotic |
| 體內(nèi)研究： |
Lincomycin (25 and 50 mg/kg, intravenously) depresses neuromuscular transmission to a degree which depended on stimulation frequencies in the rabbit sciatic nerve-gastrocnemius muscle preparation |
| 參考文獻(xiàn)： |
1. MACLEOD AJ, et al. LINCOMYCIN: A NEW ANTIBIOTIC ACTIVE AGAINST STAPHYLOCOCCI AND OTHER GRAM-POSITIVE COCCI: CLINICAL AND LABORATORY STUDIES. Can Med Assoc J. 1964 Nov 14;91:1056-60. 2. Lin AH, et al. The oxazolidinone eperezolid binds to the 50S ribosomal subunit and competes with binding of chloramphenicol and lincomycin. Antimicrob Agents Chemother. 1997 Oct;41(10):2127-31. 3. P R McMaster, et al. The effect of two chlorinated lincomycin analogues against acute toxoplasmosis in mice. Am J Trop Med Hyg. 1973 Jan;22(1):14-7. |
| 溶解性： |
DMSO : ≥ 100 mg/mL (216.92 mM) H2O : 50 mg/mL (108.46 mM; Need ultrasonic) |
| 保存條件： |
-20℃ |
| 配置溶液濃度參考： |
|
1mg |
5mg |
10mg |
| 1 mM |
2.169 ml |
10.846 ml |
21.692 ml |
| 5 mM |
0.434 ml |
2.169 ml |
4.338 ml |
| 10 mM |
0.217 ml |
1.085 ml |
2.169 ml |
| 50 mM |
0.043 ml |
0.217 ml |
0.434 ml |
|
| 注意： |
部分產(chǎn)品我司僅能提供部分信息，我司不保證所提供信息的權(quán)威性，僅供客戶參考交流研究之用。 |
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北京