產(chǎn)品描述: | Cefprozil hydrate is a second-generation cephalosporin-type antibiotic. |
靶點(diǎn): |
Antibacterial;Antibiotic;Antibacterial;?Antibiotic |
體內(nèi)研究: |
Cefprozil results in the mean peak concentration (Cmax) in infant dogs (21.2 mg/mL) and adult dogs (27.8 mg/mL). Cefprozil results in the areas under the concentration-time curve (AUC, in infant dogs: 121 mg.hr/mL, in adult dogs: 130 mg.hr/mL), half-lives (T 1/2, in infant dogs: 4.7 hours, in adult dogs: 4.7 hours) or urinary recovery rates (UR, in infant dogs: 36.3%, in adult dogs: 34.7%) between the 2 groups. |
參考文獻(xiàn): |
1.Wiseman LR, et al. Drugs,1993, 45(2), 295-317. 2.Thornsberry C, et al. Clin Infect Dis,1992, 14 Suppl 2, S189-194. 3.Ritchie DJ, et al. Clin Ther,1993, 15(1), 107-113. 4.Nakanomyo H, et al. Jpn J Antibiot,1992, 45(11), 1469-1473. |
溶解性: |
DMSO:34 mg/mL (83.45 mM) |
保存條件: |
RT |
配置溶液濃度參考: |
|
1mg |
5mg |
10mg |
1 mM |
2.454 ml |
12.272 ml |
24.543 ml |
5 mM |
0.491 ml |
2.454 ml |
4.909 ml |
10 mM |
0.245 ml |
1.227 ml |
2.454 ml |
50 mM |
0.049 ml |
0.245 ml |
0.491 ml |
|
注意: |
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