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MIR96-IN-1

    98%

MIR96-IN-1

源葉(MedMol)
S82795
1311982-88-3
C33H48N8O2
588.7866
品牌 貨號 產(chǎn)品規(guī)格 價格(RMB) 庫存（上海） 北京 武漢 南京 購買數(shù)量
源葉(MedMol) S82795-1mg 98% ￥1500.00元 預(yù)計交期：2-3天 - - -
源葉(MedMol) S82795-5mg 98% ￥3500.00元 預(yù)計交期：2-3天 - - -
源葉(MedMol) S82795-10mg 98% ￥5000.00元 預(yù)計交期：2-3天 - - -
產(chǎn)品介紹 參考文獻 質(zhì)檢證書(COA) 摩爾濃度計算器 相關(guān)產(chǎn)品

產(chǎn)品介紹

MIR96-IN-1 targets the Drosha site in the miR-96 (miRNA-96, microRNA-96) hairpin precursor, inhibiting its biogenesis, derepressing downstream targets, and triggering apoptosis in breast cancer cells. MIR96-IN-1 binds to RNAs with Kds of 1.3, 9.4, 3.4, 1.3 and 7.4 μM for RNA1, RNA2, RNA3, RNA4 and RNA5, respectively
產(chǎn)品描述： MIR96-IN-1 targets the Drosha site in the miR-96 (miRNA-96, microRNA-96) hairpin precursor, inhibiting its biogenesis, derepressing downstream targets, and triggering apoptosis in breast cancer cells. MIR96-IN-1 binds to RNAs with Kds of 1.3, 9.4, 3.4, 1.3 and 7.4 μM for RNA1, RNA2, RNA3, RNA4 and RNA5, respectively
靶點： MicroRNA;Apoptosis;MALT
體外研究： MIR96-IN-1 (Compound 1) selectively inhibits production of mature miR-96 and triggers apoptosis in breast cancer cells at micromolar concentrations. MIR96-IN-1 (Compound 3) binds a UU loop in miR-96 and inhibits its biogenesis
參考文獻： 1. Sai Pradeep Velagapudi,et al. Design of a small molecule against an oncogenic noncoding RNA. Proc Natl Acad Sci U S A. 2016 May 24;113(21):5898-903. 2. Christopher L Haga, et al. Small Molecule Inhibition of miR-544 Biogenesis Disrupts Adaptive Responses to Hypoxia by Modulating ATM-mTOR Signaling. ACS Chem Biol. 2015 Oct 16;10(10):2267-76.
溶解性： soluble  in  DMSO
保存條件： -20℃
配置溶液濃度參考：
1mg 5mg 10mg
1 mM 1.698 ml 8.492 ml 16.984 ml
5 mM 0.34 ml 1.698 ml 3.397 ml
10 mM 0.17 ml 0.849 ml 1.698 ml
50 mM 0.034 ml 0.17 ml 0.34 ml
注意： 部分產(chǎn)品我司僅能提供部分信息，我司不保證所提供信息的權(quán)威性，僅供客戶參考交流研究之用。

參考文獻

質(zhì)檢證書(COA)

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批號：JS298415 貨號：S20001-25g
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摩爾濃度計算器

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