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Gamithromycin (ML-1709460)

98%

(2R,3S,4R,5S,8R,10R,11R,12S,13S,14R)-13-[(2,6-dideoxy-3-Cmethyl-3-O-methyl-a-L-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,8,10,12,14-hexamethyl-7-propyl-11-[[3,4,6-trideoxy-3-(dimethylamino

產(chǎn)品說明書

品牌：源葉(MedMol)

產(chǎn)品編號：S83403 一鍵復(fù)制產(chǎn)品信息

CAS號：145435-72-9

分子式：C₄₀H₇₆N₂O₁₂

分子量：777.038

別名：加米霉素;GAMITHROMYCIN;(2R,3S,4R,5S,8R,10R,11R,12S,13S,14R)-13-[(2,6-dideoxy-3-Cmethyl-3-O-methyl-a-L-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,8,10,12,14-hexamethyl-7-propyl-11-[[3,4,6-trideo

貨號	規(guī)格	價格	上海	北京	武漢	南京
S83403-5mg	98%	￥240.00 S83403-5mg ￥240.00 現(xiàn)貨	1773 >10	-	-	-
S83403-10mg	98%	￥360.00 S83403-10mg ￥360.00 現(xiàn)貨	891 >10	-	-	-
S83403-50mg	98%	￥800.00 S83403-50mg ￥800.00 現(xiàn)貨	182 >10	-	-	-
S83403-250mg	98%	￥1800.00 S83403-250mg ￥1800.00 現(xiàn)貨	35 >10	-	-	-

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產(chǎn)品介紹參考文獻質(zhì)檢證書(COA) 摩爾濃度計算器相關(guān)產(chǎn)品

產(chǎn)品介紹

Gamithromycin is an antimicrobial agent which can inhibit the growth of MmmSC strains B237 and Tan8 with MICs of 0.00012 and 0.00006 μg/mL, respectively.

產(chǎn)品描述：

Gamithromycin is an antimicrobial agent which can inhibit the growth of MmmSC strains B237 and Tan8 with MICs of 0.00012 and 0.00006 μg/mL, respectively.

靶點：

MIC: 0.00012 μg/mL (MmmSC strain B237), 0.00006μg/mL (MmmSC strain Tan8);Antibacterial;?Antibiotic

體內(nèi)研究：

The proportion of foals that recover without the need for a change in treatment is significantly (P<0.048) higher for foals treated with Gamithromycin (GAM) (38 of 40; 95%) or AZM-RIF (39 of 40; 98%) compare to control foals (32 of 41; 78%). The clinical scores, number of abscesses and the abscess scores after 1 and 2 weeks of treatment are significantly lower for foals treated with Gamithromycin (GAM) or AZM-RIF compare to control foals. The WBC count of foals treated with Gamithromycin (GAM) is significantly higher than that of foals treated with AZM-RIF on week 3 of treatment

參考文獻：

1. Mitchell JD, et al. In vitro pharmacodynamics of gamithromycin against Mycoplasma mycoides subspecies mycoides Small Colony. Vet J. 2013 Sep;197(3):806-11. 2. F. Hildebrand, et al. Efficacy of Gamithromycin for the Treatment of Foals with Mild to Moderate Bronchopneumonia. J Vet Intern Med. 2015 Jan-Feb; 29(1): 333–338.

溶解性：

DMSO : 100 mg/mL (128.69 mM; Need ultrasonic)

保存條件：

2-8℃

配置溶液濃度參考：

	1mg	5mg	10mg
1 mM	1.287 ml	6.435 ml	12.869 ml
5 mM	0.257 ml	1.287 ml	2.574 ml
10 mM	0.129 ml	0.643 ml	1.287 ml
50 mM	0.026 ml	0.129 ml	0.257 ml

注意：

部分產(chǎn)品我司僅能提供部分信息，我司不保證所提供信息的權(quán)威性，僅供客戶參考交流研究之用。

參考文獻

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